Porous oligolactide-hydroxyapatite composite scaffolds were obtained by stereolithographic fabrication. Gentamicin was then\ncoated on the scaffolds afterwards, to achieve antimicrobial delivery ability to treat bone infection. The scaffolds examined by\nstereomicroscope, SEM, and �¼CT-scan showed a well-ordered pore structure with uniform pore distribution and pore\ninterconnectivity. The physical and mechanical properties of the scaffolds were investigated. It was shown that not only porosity\nbut also scaffold structure played a critical role in governing the strength of scaffolds. A good scaffold design could create proper\norientation of pores in a way to strengthen the scaffold structure. The drug delivery profile of the porous scaffolds was also\nanalyzed using microbiological assay. The release rates of gentamicin from the scaffolds showed prolonged drug release at the\nlevels higher than the minimum inhibitory concentrations for S. aureus and E. coli over a 2-week period. It indicated a potential\nof the scaffolds to serve as local antibiotic delivery to prevent bacterial infection.
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